ATP-dependent Proteolysis in Mitochondria
نویسندگان
چکیده
منابع مشابه
Regulation of ATP-ubiquitin-dependent proteolysis in muscle wasting.
Protein breakdown plays a major role in muscle growth and atrophy. However, the regulation of muscle proteolysis by nutritional, hormonal and mechanical factors remains poorly understood. In this review, the methods available to study skeletal muscle protein breakdown, and our current understanding of the role of 3 major proteolytic systems that are well characterized in this tissue (ie the lys...
متن کاملThe ATP-dependent breakdown of proteins in mammalian mitochondria.
turnover, but seems unlikely as proteinase 1 is probably lysosomal (North, 19826). Nor has it been shown that substrates and inhibitors used in these studies are specific for proteinase I, which raises the possibility that other proteinases might be involved. A role for cysteine proteinases in the selective control of turnover rates of specific proteins requires more thorough investigation. It ...
متن کاملPentoxifylline inhibits Ca2+-dependent and ATP proteasome-dependent proteolysis in skeletal muscle from acutely diabetic rats.
Previous studies from this laboratory have shown that catecholamines exert an inhibitory effect on muscle protein degradation through a pathway involving the cAMP cascade. The present work investigated the systemic effect of pentoxifylline (PTX; cAMP-phosphodiesterase inhibitor) treatment on the rate of overall proteolysis, the activity of proteolytic systems, and the process of protein synthes...
متن کاملPentoxifylline inhibits Ca -dependent and ATP proteasome-dependent proteolysis in skeletal muscle from acutely diabetic rats
Baviera AM, Zanon NM, Navegantes LC, Migliorini RH, Kettelhut IC. Pentoxifylline inhibits Ca -dependent and ATP proteasomedependent proteolysis in skeletal muscle from acutely diabetic rats. Am J Physiol Endocrinol Metab 292: E702–E708, 2007. First published October 31, 2006; doi:10.1152/ajpendo.00147.2006.—Previous studies from this laboratory have shown that catecholamines exert an inhibitory...
متن کاملThe Copper Efflux Regulator CueR Is Subject to ATP-Dependent Proteolysis in Escherichia coli
The trace element copper serves as cofactor for many enzymes but is toxic at elevated concentrations. In bacteria, the intracellular copper level is maintained by copper efflux systems including the Cue system controlled by the transcription factor CueR. CueR, a member of the MerR family, forms homodimers, and binds monovalent copper ions with high affinity. It activates transcription of the co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.32.20596